Searchable abstracts of presentations at key conferences in endocrinology

ea0044p31 | Adrenal and Steroids | SFEBES2016

Maternal smoking disrupts adrenal steroid production in the human fetus

Johnston Zoe , Bellingham Michelle , Hough Denise , Filis Panagiotis , O'Shaughnessy Peter , Fowler Paul

Introduction: The adrenal gland dominates in human fetal steroid endocrinology and produces large amounts of Δ5 androgens. Adrenal development in the human is poorly understood, and species differences make animal models only partially relevant. In this study we measured the steroid content of the human adrenal during fetal development and determined whether maternal smoking affects adrenal steroid concentrations or associated steroidogenic enzymes....